Publications

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Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking.
Konya V, Ullen A, Kampitsch N, Theiler A, Philipose S, Parzmair GP, Marsche G, Peskar BA, Schuligoi R, Sattler W, Heinemann A.J Allergy Clin Immunol. 2012 Jun 14. [Epub ahead of print]

Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow
Stephen Paul Samuel, Namrata Jain, Frank O'Dowd, Toby Paul, Dmitry Kashanin, Valerie A Gerard, Yurii K Gun'ko, Adriele Prina-Mello, Yuri Volkov.
International Journal of Nanomedicine 2012:7 2943-2956 Published online 13 June 2012

L-Plastin Regulates Polarization and Migration in Chemokine-Stimulated Human T Lymphocytes
Michael Freeley, Francis O'Dowd, Toby Paul, Dmitry Kashanin, Anthony Davies, Dermot Kelleher, Aideen Long.
J Immunol; 2012, 1103242: Prepublished online 11 May 2012

PGH1, the Precursor for the Anti-Inflammatory Prostaglandins of the 1-series, is a Potent Activator of the Pro-Inflammatory Receptor CRTH2/DP2
Ralf Schröder, Luzheng Xue, Viktoria Konya, Lene Martini, Nora Kampitsch, Jennifer L. Whistler, Trond Ulven, Akos Heinemann, Roy Pettipher, Evi Kostenis PLoS ONE 7(3): e33329.  Published 19 March 2012

Proteinase 3 Contributes to Transendothelial Migration of NB1-Positive Neutrophils
Christopher J. Kuckleburg, Sarah B. Tilkens, Sentot Santoso and Peter J. Newman J Immunol; 2012, 188: Prepublished online 20 January 2012

Flow chamber based assays to measure thrombus formation in vitro:  requirements for standardization.
Roest M., Reininger A., Zwaginga J.J., King M.R., Heemskerk J.W.M., the Biorheology Subcommittee of the SSC of the ISTH. J Thromb Hamost 2011;9:2322-4
 
Interleukin-33 Induces Expression of Adhesion Molecules and Inflammatory Activation in Human Endothelial Cells and In Human Atherosclerotic Plaques.
Svitlana Demyanets, Viktoria Konya, Sefan P. Kastl, Christoph Kaun, Sabine Rauscher, Alexander Niessner, Richard Pentz, Stefan Pfaffenberger, Kathrin Rychli, Christof E. Lemberger, Rainer de Martin, Akos Heinemann, Ihor Huk, Marion Groger, Gerald Maurer, Kurt Huber, Johann Wojta Arterioscler Thromb Vascular Biol 2011;31:2080-2089

Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors.
Viktoria Konya, Sonia Philipose, Zoltan Balint, Andrea Olschewski, Gunther Marsche, Eva M. Sturm, Rudolf Schicho, Bernhard A. Peskar, Rufina Schuligoi and Akos Heinemann Eur J. Immunol. 2011 Aug;41(8):2379-89

Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protecitve IgG epitopes in infected erythrocyte surface-exposed PfEMP1. Lea Barfod, Michael B. Dalgaard, Suzan T. Pleman, Michael F. Ofori, Richard J. Pleass and Lars Hviid PNAS July 11, 2011, doi:10.10735/pnas.1103708108

Inositol hexakisphophate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-triphosphate signaling. Amit Prasad, Yonghui Jia, Anutosh Chakraborty, Yitang Li, Supriya K Jain, Jia Zhong, Saurabh Ghosh Roy, Fabien Loison, Subhanjan Mondal, Jiro Sakai, Catlyn Blanchard, Solomon H Snyder and Hongbo R Luo Nature Immunology, 2011, Published online 19 June 2011

Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells. Abel Sanchez-Aguilera, Yun-Jung Lee, Cristina Lo Celso, Francesca Ferraro, Kristina Brumme, Subhanjan Mondal, Chaekyun Kim, Adrienne Dorrance, Hongbo R. Luo, David T. Scadden and David A. Williams. PNAS May 2, 2011, www.pnas.org/cgi/doi/10.1073/pnas.1102018108

Chondroitin Sulfate A-Adhering Plasmodium falciparum-Infected Erythrocytes - Express Functionally Important Antibody Epitopes Shared by Multiple Variants. Lea Barfod, Tina Dobrilovic, Pamela Magistrado, Pongsak, KhunraeFirmine Viwami, Jonas Bruun, Madeleine Dahlback, Nadia L. Bernasconi, Michal Fried, Davis John, Patrick E. Dufy, Ali Salanti, Antonio Lanzavecchia, Chwee Teck Lim, Nicaise Tuikue Ndam, Matthew K. Higgins and Lars Hviid. The Journal of Immunology, 2010, 185: 7553-7561

The Prostaglandin E2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation. Sonia Philipose; Viktoria Konya; Ivana Sreckovic; Gunther Marsche; Irmgard T. Lippe; Bernhard A. Peskar; Akos Heinemann; Rufina Schuligoi Arteriosclerosis, Thrombosis, and Vascular Biology. 2010;30:2416

A small-molecule inhibitor of integrin alpha2 beta1 introduces a new strategy for antithrombotic therapy. Nissinen L., Pentikainen OT., Jouppila A., Kapyla J., Ojala M., Nieminen J., Lipsanen A., Lappalainen H., Eckes B., Johnson MS., Lassila R., Marjamaki A., Heino J. Thromb Haemost. 2010 Feb 1;103(2):387-97.  Epub 2009 Dec 1

Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment. Eun Young Choi.,  Emmanouil Chavakis.,  Marcus A. Czabanka.,  Harald F. Langer., Line Fraemohs., Matina Economopoulou., Ramendra K. Kundu., Alessia Orlandi., Ying Yi Zheng., DaRue A. Prieto.,  Christie M. Ballantyne.,  Stephanie L. Constant.,  William C. Aird., Thalia Papayannopoulou., Carl G. Gahmberg.,  Mark C. Udey.,  Peter Vajkoczy., Thomas Quertermous.,  Stefanie Dimmeler., Christian Weber., Triantafyllos Chavakis. Science Volume 322, 14th November 2008

Montelukast inhibition of resting and GM-CSF-stimulated eosinophil adhesion to VCAM-1 under flow conditions appears independent of cysLT1R antagonism. Robinson A. J., Kashanin D., O'Dowd F., Williams V., Walsh G. M. Journal of Leukocyte Biology Volume 83, June 2008

A new antihistamine levocetirizine inhibits eosinophil adhesion to vascular cell adhesion molecule-1 under flow conditions. Wu P., Mitchell S., Walsh G.M. Clin. Exp. Allergy 2005; 35:1073-1079

A multidisciplinary approach to the study of T cell migration. Long A., Mitchell S., Kashanin D., Williams V., Prina Mello A., Shvets I., Kelleher D., Volkov Y. Ann. N. Y. Sci. 1028: 313-319 (2004)

Microfluidics Enabling Platform for Cell-based Assays. Williams V., Kashanin D., Shvets I.V., Mitchell S., Volkov Y., Kelleher D. JALA Vol. 7, No. 6, December 2002