Vena8 Endothelial+ Biochips

Ideal for studying cell-cell interaction studies, cell rolling and adhesion studies, and mimicking in-vivo physiological flow

Set-up

Each Vena8 Endothelial+ biochip contains 8 parallel enclosed microcapillaries for culturing primary endothelial cells or coating with proteins and continuous flow cell based assays.
Primary endothelial cells are cultured and cell suspensions may then be injected using the Kima or Mirus Evo Nanopump which supports a range of shear stresses / shear flow rates for dynamic flow based assays.

It is possible to culture 8 cell monolayers simultaneously over 24-48 hours.
 

Practical

Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls.

Ideal for use with phase contrast imaging and fluorescence imaging to study cell-cell interactions under conditions mimicking physiological flow.

 

Dimensions 800um (width) x 120um (depth) x 20mm (length)
No. of channels 8
Substrate Thickness 0.5mm
Sizes Sample Pack of 2 (16 assays, Pack of 5 (40 assays), Pack of 10 (80 assays) or Mixed Pack

Features

In motion

Inflammation - Atherosclerosis:
THP-1 monocytes adhering to HUVECs in biochip under flow

 


 

Atherosclerosis:
Primary monocyte adhesion to coronary artery endothelium under shear flow

 

Useful documents


If you wish to receive a copy of these documents, contact us at: mycells@tebu-bio.com
 

 

 

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